i honestly would recommend the comp cams xtreme energy cam, they have lots to choose from, they are a dual profile cam, and give you great throttle response and alot of vacuum, that is the cam im running in my 383 with some aluminum heads, and i literally burnout yesterday down an entire block in 1st 2nd and 3 gear lol. it and that thing is touchy, i was litterally only a litte over 1/4 down on the throttle the whole time. it has a decent idle to it also, an xtreme engery would be good in a 350, as far as tranny, i dont know a whole lot about manual so ill leave that to another member :yes: