In a nutshell... the answer is yes. I did a complete front end alignment in my garage a few years ago on my Nova (Caster, Camber, and Toe-in).
My results: Castor
Driver: 5° Positive
Pass: 5.5° Positive (.5 more to help with road crown drift) Camber: 1/2° negative (both wheels) Toe in: 1/16" "
My car runs straight with no drifting, the steering wheels stays centered, I have good return of the steering wheel to center position after a turn, and my tire wear has been excellent.
You need to have:
* A level garage floor (or a way to level your car within your garage).
* Some type of turn plates that go under your front tires (with the weight of the vehicle on all of the tires). I made my own turn plates.
* A digital level... or a decent front end alignment tool that can be attached to the face of the front wheel - parallel with the wheel rim.
* A way to measure when your tire/wheel is turned 20° both left and right.